MedCalc statistical program

MedCalc for Windows description

Data management

• Integrated spreadsheet with 16384 columns and up to 100000 rows.
• Correct handling of missing data.
• Outliers can easily be excluded.
• Built-in WYSIWYG text editor.
• Imports Excel, Excel 2007, SPSS, DBase and Lotus files, and files in SYLK, DIF or plain text format.
• Easy selection of subgroups for statistical analysis.

Documentation

• Comprehensive help file.
• Manual in PDF format (go to download area).
• Complete HTML manual on MedCalc web site.
• Context help in dialog boxes.

ROC curve analysis

• Area under the curve (AUC) with standard error, 95% confidence interval, P-value. Offers choice between methodology of DeLong et al. (1988) and Hanley & McNeil (1982, 1983).
• List of sensitivity, specificity, likelihood ratios, and positive and negative predictive values for all possible threshold values.
• ROC curve graph with 95% Confidence Bounds.
• Threshold values can be selected in an interactive dot diagram with automatic calculation of corresponding sensitivity and specificity.
• Plot of sensitivity and specificity versus criterion values.
• Interval likelihood ratios.
• Comparison of up to 6 ROC curves: difference between the areas under the ROC curves, with standard error, 95% confidence interval and P-value.
• Sample size calculation for area under ROC curve and comparison of ROC curves.
• Go to the ROC curve analysis section of the MedCalc manual for more information on ROC curve analysis in MedCalc.

Graphs

• Lots of graphs, see Graph gallery.
• Data point identification in graphs.
• Draw text boxes, lines, arrows and connectors.
• Name, save and recall graphs and statistics.
• Statistical info in graph windows.
• Save graphs as BMP, PNG, GIF, PCX, JPG or TIF files, or as PowerPoint slides (*.pptx).

System requirements

• PC with WINDOWS XP, Windows Server 2003, Windows Vista, Windows 7 or Windows 8 (32-bit and 64-bit versions).
• 512 Mb of memory.
• 20 Mb free space on the hard disk. 

Statistical features

   

Statistical features

• Summary statistics
• Outlier detection
• Distribution plots
  • Histogram
  • Cumulative frequency distribution
  • Normal plot
  • Dot plot
  • Box-and-whisker plot
• Correlation
  • Correlation coefficient
  • Partial correlation
  • Rank correlation
  • Scatter diagram
• Regression
  • Regression
  • Scatter diagram & regression line
  • Multiple regression
  • Logistic regression
  • Nonlinear regression
• T-tests
  • One sample t-test
  • Independent samples t-test
  • Paired samples t-test
• Rank sum tests
  • Signed rank sum test (one sample)
  • Mann-Whitney test (independent samples)
  • Wilcoxon test (paired samples)
• Variance ratio test (F-test)
• Anova …
  • One-way analysis of variance
  • Two-way analysis of variance
  • Analysis of covariance
  • Repeated measures analysis of variance
  • Kruskal-Wallis test
  • Friedman test
• Crosstabs (categorical data)
  • Frequency table & Chi-squared test
  • Fisher’s exact test
  • McNemar test
  • Cochran’s Q test
  • Relative risk & Odds ratio
  • Frequencies bar charts
• Survival analysis
  • Kaplan-Meier survival curves
  • Cox proportional-hazards regression
• Serial measurements
• Reference intervals
  • Reference interval
  • Age-related reference interval
• Method comparison & evaluation
  • Bland & Altman plot
  • Bland-Altman plot with multiple measurements per subject
  • Mountain plot
  • Deming regression
  • Passing & Bablok regression
  • Coefficient of variation from duplicate measurements
• Agreement & responsiveness
  • Intraclass correlation coefficient
  • Concordance correlation coefficient
  • Inter-rater agreement (kappa)
  • Cronbach’s alpha
  • Responsiveness
• ROC curve analysis
  • ROC curve analysis
  • Interactive dot diagram
  • Plot versus criterion values
  • Predictive values
  • Interval likelihood ratios
  • Comparison of ROC curves
• Create tables
  • Summary statistics table
  • Correlation table
• Meta-analysis
  • Introduction
  • Continuous measure
  • Correlation
  • Proportion
  • Relative risk
  • Risk difference
  • Odds ratio
  • Area under ROC curve
• Tests on summarized data
  • Test for one mean
  • Test for one proportion
  • Chi-squared test
  • Fisher’s exact test for a 2×2 table
  • McNemar test on paired proportions
  • Comparison of means (t-test)
  • Comparison of standard deviations (F-test)
  • Comparison of correlation coefficients
  • Comparison of two proportions
  • Comparison of areas under independent ROC curves
  • Confidence interval for a rate
  • Comparison of two rates
  • Relative risk
  • Odds ratio
  • Inter-rater agreement
  • Diagnostic test
  • Likelihood ratios (2xk table)
• Sample size calculation
  • Single mean
  • Single proportion
  • Comparison of two means
  • Comparison of two proportions
  • Correlation coefficient
  • Area under ROC curve
  • Comparison of two ROC curves
  • Survival analysis (logrank test)
• More graphs
• Data comparison graphs
• Multiple comparison graphs
• Clustered multiple comparison graphs
• Multiple variables graphs
• Clustered multiple variables graphs
• Multiple line graph
• Control chart
• Youden plot
• Polar plot
• Forest plot
• Function plot

Software Accessibility

MedCalc Software is committed to providing high-quality products and services that are both useful and accessible to all potential users, including individuals with disabilities. As such, we support the goals of Section 508 of the U.S. the Rehabilitation Act.

Section 508 of that act sets standards for software developers so that software users with disabilities can use software in a way that is comparable to the use by individuals without disabilities. MedCalc Software aims to comply with these standards.

Section 508 Standards

Subpart B — Technical Standards

§ 1194.21 Software applications and operating systems

(a)	When software is designed to run on a system that has a keyboard, product functions shall be executable from a keyboard where the function itself or the result of performing a function can be discerned textually.
(b)	Applications shall not disrupt or disable activated features of other products that are identified as accessibility features, where those features are developed and documented according to industry standards. Applications also shall not disrupt or disable activated features of any operating system that are identified as accessibility features where the application programming interface for those accessibility features has been documented by the manufacturer of the operating system and is available to the product developer.
(c)	A well-defined on-screen indication of the current focus shall be provided that moves among interactive interface elements as the input focus changes. The focus shall be programmatically exposed so that assistive technology can track focus and focus changes.
(d)	Sufficient information about a user interface element including the identity, operation and state of the element shall be available to assistive technology. When an image represents a program element, the information conveyed by the image must also be available in text.
(e)	When bitmap images are used to identify controls, status indicators, or other programmatic elements, the meaning assigned to those images shall be consistent throughout an application’s performance.
(f)	Textual information shall be provided through operating system functions for displaying text. The minimum information that shall be made available is text content, text input caret location, and text attributes.
(g)	Applications shall not override user selected contrast and color selections and other individual display attributes.
(h)	When animation is displayed, the information shall be displayable in at least one non-animated presentation mode at the option of the user.
(i)	Color coding shall not be used as the only means of conveying information, indicating an action, prompting a response, or distinguishing a visual element.
(j)	When a product permits a user to adjust color and contrast settings, a variety of color selections capable of producing a range of contrast levels shall be provided.
(k)	Software shall not use flashing or blinking text, objects, or other elements having a flash or blink frequency greater than 2 Hz and lower than 55 Hz.
(l)	When electronic forms are used, the form shall allow people using assistive technology to access the information, field elements, and functionality required for completion and submission of the form, including all directions and cues.

	Some accessibility issues
	Full compliance

Feedback

If you do discover some accessibility problems please let us know by emailing: info@medcalc.org

Download MedCalc Version 14.12.0

You can run the software, without any feature limitations, during 15 days without registration.

After this trial period you should purchase a MedCalc license so you can continue to use the software.

Item	Server:	USA	Europe
MedCalc setup file 32-bits medcalcsetup32.msi (14.59 MB)
MedCalc setup file 64-bits medcalcsetup64.msi (15.4 MB)

Download and installation instructions

• The software is available in different versions for 32-bits and 64-bits Windows editions. The 32-bits version will work on both Windows editions. The 64-bits version will work on 64-bits Windows editions only.
• In order to download, you may need to use the “Save Target as…” or “Save to Disk” commands of your Web browser after right-clicking the download link.
• The installation files are suitable for new installations only as well as software updates.
• If you have previously installed MedCalc, you must close any open (running) copy of MedCalc first. Then execute medcalcsetup[32/64].msi and follow the instructions for the installation procedure.
• If you want to install the 64-bits version and you have a 32-bits MedCalc version already installed, you should first remove that older MedCalc version through your Windows control panel.
• How to determine whether a computer is running a 32-bit version or 64-bit version of the Windows operating system (link to Microsoft website).
• Anti-virus programs can sometimes interfere with the installation process. Temporarily disabling your anti-virus program may help if you’re having trouble with your installation. You should re-enable it as soon as installation has been completed.

New: MedCalc file viewer

With the MedCalc file viewer you can open MedCalc files (*.mc1) without the need for a MedCalc license.

Item	Server:	USA	Europe
MedCalc viewer setup file 32-bits medcalcviewersetup32.msi (6.19 MB)
MedCalc viewer setup file 64-bits medcalcviewersetup64.msi

MedCalc manual

The MedCalc manual (274 pages, version 14.8.1) is in Adobe Acrobat PDF format. You need Acrobat Reader to be able to read this file.

Item	Server:	USA	Europe
MedCalc manual (PDF) medcalcmanual.pdf (7.85 MB)